Teenage fugitives Nico, Gert, Karolina, Chase and Molly are survivors. After learning their parents were super villains, the kids discover special skills of their own and topple their parents' criminal empire. Now, the Runaways meet Victor Mancha, the unknowing son of another infamous super villain, as a meddling ex-super hero support group tries to force the Runaways off the streets! Meanwhile, one Runaway deals with an unexpected legacy, and the...

"Midwife Clara Perry is accustomed to comforting her pregnant patients, calming fathers-to-be as they anxiously await the birth of their children, and ensuring the babies she delivers come safely into the world. But when Clara's life takes a nosedive, she realizes she hasn't been tending to her own needs and does something drastic: she runs away and starts over again in a place where no one knows her or the mess she's left behind in West Virginia....

When the Runaways eliminate the Pride from Los Angeles, it leaves a vacuum of power in the city's underworld, and soon Nico, Karolina, Gert, Chase, and Molly are on the run again to uncover the truth behind their parents' past before it catches up to them.